February 24, 2015

A blood test determines the best therapy to quit smoking

A simple blood test could help to select the most appropriate therapy for smoking cessation in each individual. According to a team from the University of Pennsylvania blood test provides key information: the speed which nicotine is metabolized at. That determines the time nicotine stays in the body.

smokingAbout 60% of people who want to quit smoking just give up in the first 7 days. There has long been speculated that there was a genetic predisposition that makes it easier to quit for some people, but there is little data about it. Therefore, most smokers do not receive the most appropriate therapy to quit, but that test had not a scientific basis.

Now thanks to the data of this work each smoker can select the appropriate therapy. The study, which analyzed 1,240 smokers who had tried any of the various systems to quit smoking – nicotine patches or gum, drugs, etc., researchers have seen the speed at which nicotine is metabolized indicates which treatment may be most effective.

So for example, the researchers have found that in those who have a ‘normal’ rate of metabolism therapy choice should be the varenicline drug (Chantix) because if treated with nicotine patches have great potential to return to smoking within six months. However, the ‘slower metabolizers’ would be more advisable to use the nicotine patch is that although it has the same success rate replacement therapy with varenicline nicotine, has far fewer side effects.

The research determines the most appropriate treatment based on the rate at which smokers metabolize nicotine could be a viable to help guide the choice of smoking strategy and, ultimately, improve quit rates and will serve to optimize the dropout rates of all smokers, while minimizing side effects. Also remember that a blood test is a simple test that could be applied in clinical practice without problems

The results of this study represent a major breakthrough, should be replicated. And, if achieved, could lead to significant changes in clinical practice.

Category : Smoking